Sleepy Creek is a tributary of the Potomac River in the United States, belonging to the Chesapeake Bay's watershed. Sleepy Creek's source lies near the Hampshire County, West Virginia border at Good, north of State Route 127 in Frederick County, Virginia. From Frederick County, Sleepy Creek flows north through Morgan County, West Virginia where it drains into the Potomac at the community of Sleepy Creek on the old Baltimore & Ohio Railroad mainline. While Sleepy Creek Lake is a part of the Sleepy Creek watershed, it is an impoundment of its tributary, Meadow Branch, in Berkeley County and not of Sleepy Creek itself.